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The utilization of new human 3D lung models in combination with the latest gene expression technologies to evaluate the effects of conventional cigarette smoke versus electronic cigarette aerosols demonstrates how in vitro models can be used to understand biological effects, says Jim McKim, PhD, Editor-in-Chief of Applied In Vitro Toxicology and Founder and CEO, IonTox, LLC

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Meanwhile, data from Statista estimates the global tobacco market to be worth over US$900 billion, with cigarettes continuing to account for the largest share despite the rise of alternative nicotine products

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